一念三千-混凝土纤维
替格瑞洛致咯血
叶振;罗富良;马双双;蔡伦;曹胜;童德银
【期刊名称】《药物不良反应杂志》
【年(卷),期】2017(019)005
【摘要】A 70-year-old male patient received ticagrelor 90 mg twice
daily and aspirin 100 mg once daily as dual antiplatelet therapy after
operation for coronary stent implanting. On day 2 of treatment,he
developed traces of blood in sputum. The hemoptysis became worse
and times became more after that. On day 42,the patient developed
massive hemoptysis about 100 ml. Ticagrelor was discontinued by
himself. The patient then was given oxygen inhalation,expectorant drug
and hemostatic agents. Anticoagulant therapy was adjusted for the
combined use of clopidogrel 75 mg once daily and aspirin 100 mg once
daily. On day 4 of the ticagrelor withdrawal,the amount of hemoptysis
was obviously reduced. On day 7,the hemoptysis ceased.%1例70岁男性
患者冠状动脉支架植入术后接受替格瑞洛(90 mg口服、2次d)和阿司匹林肠
溶片(100 mg口服、1次d)双联抗血小板治疗.用药第2天患者发现痰中带少
许血丝;此后数次出现唾液中带血丝;第42天突发大咯血,咯血量约100 ml.自行
停用替格瑞洛.入院后给予吸氧、祛痰、止血等治疗,抗凝治疗调整为硫酸氢氯吡
格雷(75 mg口服、1次d)与阿司匹林肠溶片(剂量同前)联用.停用替格瑞洛第
4天患者咯血量明显减少;第7天咯血停止.
【总页数】2页(387-388)
【关键词】咯血;替格瑞洛
【作者】叶振;罗富良;马双双;蔡伦;曹胜;童德银
【作者单位】 江苏省宿迁市第一人民医院药学部; 中国医学科
学院北京协和医学院阜外医院心血管植入材料临床前研究评价北京市重点实验
室; 江苏省宿迁市第一人民医院药学部; 江苏省宿迁市第一人民
医院药学部; 江苏省宿迁市第一人民医院药学部; 江苏省宿迁市
第一人民医院药学部
【正文语种】中文
【中图分类】
【文献来源】
https:demic-journal-cn_adverse-drug-
reactions-journal_
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demic-journal-cn_adverse-drug-reactions-journal_ 【相关文献】 1.手性固定相HPLC法测定替格瑞洛片中替格瑞洛异构体含量 [J]
demic-journal-cn_adverse-drug-reactions-journal_ 【相关文献】 1.手性固定相HPLC法测定替格瑞洛片中替格瑞洛异构体含量 [J]
the amount of hemoptysis was obviously reduced. On day 7
TANG Li; 唐利; DU Xiao; 杜潇 4.替格瑞洛联用重组人组织型纤溶酶原激酶衍生物致颅内出血 [C]
止血等治疗
期】2017(019)005 【摘要】A 70-year-old male patient received ticagrelor 90 mg twice daily and aspirin 100 mg once daily as dual antiplatelet therapy after operation for coronary stent implanting. On day 2 of treatment
the patient developed massive hemoptysis about 100 ml. Ticagrelor was discontinued by himself. The patient then was given oxygen inhalation
the patient developed massive hemoptysis about 100 ml. Ticagrelor was discontinued by himself. The patient then was given oxygen inhalation
止血等治疗
王瑾; 赵森; 曹平辉; 韩福生; 曾玉杰; 何华 3.替格瑞洛联合他汀类药物致肌病横纹肌溶解的信号检测与分析 [C]
the hemoptysis ceased.%1例70岁男性患者冠状动脉支架植入术后接受替格瑞洛(90 mg口服